Journal article
25-Hydroxyvitamin D concentration and all-cause mortality: The Melbourne Collaborative Cohort Study
AK Heath, EJ Williamson, D Kvaskoff, AM Hodge, PR Ebeling, L Baglietto, RE Neale, GG Giles, DW Eyles, DR English
Public Health Nutrition | CAMBRIDGE UNIV PRESS | Published : 2017
Abstract
Objective To investigate relationships between mortality and circulating 25-hydroxyvitamin D (25(OH)D), 25-hydroxycholecalciferol (25(OH)D3) and 25-hydroxyergocalciferol (25(OH)D2). Design Case-cohort study within the Melbourne Collaborative Cohort Study (MCCS). We measured 25(OH)D2 and 25(OH)D3 in archived dried blood spots by LC-MS/MS. Cox regression was used to estimate mortality hazard ratios (HR), with adjustment for confounders. Setting General community. Subjects The MCCS included 29 206 participants, who at recruitment in 1990-1994 were aged 40-69 years, had dried blood spots collected and no history of cancer. For the present study we selected participants who died by 31 December 20..
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Awarded by National Health and Medical Research Council
Funding Acknowledgements
Cohort recruitment was funded by VicHealth and The Cancer Council Victoria. This work was supported by the National Health and Medical Research Council (project grant 623208). A.K.H. is supported by an Australian Postgraduate Award. The funding source had no role in the design, analysis or writing of this article.